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Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration

Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration | March 2021 | Rheumatology Rodrigo Coutinho de Almeida, Ahmed Mahfouz, Hailiang Mei, Evelyn Houtman, Wouter den Hollander, Jamie Soul, Eka Suchiman, Nico Lakenberg, Jennifer Meessen, Kasper Huetink ... Show more Abstract Objective To identify OA subtypes based on cartilage transcriptomic data in cartilage tissue and characterize their underlying pathophysiological processes and/or [...]

By |2021-09-21T12:35:43+00:00September 15th, 2021|Papers artrose|0 Comments
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Families in comparison: An individual-level comparison of life-course and family reconstructions between population and vital event registers

Families in comparison: An individual-level comparison of life-course and family reconstructions between population and vital event registers | 12-02-2020 | A Journal of Demography Niels van den Berg, Ingrid K. van Dijk, Rick J. Mourits, P. Eline Slagboom, Angelique A.P.O. Janssens & Kees Mandemakers Identifying genes that code for proteins associated to longevity is [...]

By |2021-09-14T14:48:58+00:00September 14th, 2021|Papers ageing|0 Comments
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Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian

Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian | 12-11-2020 | Leukemia Erik B. van den Akker, Stavros Makrodimitris, Marc Hulsman, Martijn H. Brugman, Tatjana Nikolic, Ted Bradley, Quinten Waisfisz, Frank Baas, Marja E. Jakobs, Daphne de Jong, P. Eline Slagboom, Frank J. T. Staal, Marcel J. T. Reinders & Henne Holstege Age-related Clonal hematopoiesis (ARCH) is an inevitable consequence of ageing, which arises when [...]

By |2021-09-21T12:35:16+00:00September 14th, 2021|Uncategorized|0 Comments
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Prize for prof. Eline Slagboom

Prof. Eline Slagboom received the Karl Ludwig Schoberprice for leading ageing research. On Friday September 10th 2021 prof. Eline Slagboom received the Schober prize in Halle, Germany. Since 2003, the Karl Ludwig Schober Prize has been awarded every two years to renowned geriatric researchers. Karl-Ludwig Schober (July 13, 1912 – † October 11, 1999) was a German surgeon and professor [...]

By |2021-09-13T08:43:05+00:00September 13th, 2021|News|0 Comments
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Impact of genetics on epigenetics published in Nature Genetics – September 6th 2021

Nature Genetics | September 6th 2021 Impact of genetics on epigenetics published in Nature Genetics Nature Genetics this week published the result of a major international study to chart the impact of genetics on DNA methylation, a key epigenetic mark. It was the result of an effort by more than 150 scientists of 50 [...]

By |2021-09-10T12:45:49+00:00September 10th, 2021|News, Papers epigenetica|0 Comments
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De eerste 1.000 dagen beïnvloeden het hele leven – NRC augustus 2021

NRC | 20 augustus 2021 | auteur Niki Korteweg Gezonde kinderen Een slechte start in de eerste duizend dagen na de conceptie zet een kind een leven lang op achterstand. Veel risicofactoren gaan samen: roken, drinken, stress… „Maar jonge kinderen hebben een enorme veerkracht.”\ Lees het artikel op de website van het NRC [...]

By |2021-09-21T12:36:04+00:00August 25th, 2021|News|0 Comments
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Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants

Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants | 16-08-2021 | BMC Evelyn Houtman, Margo Tuerlings, Janne Riechelman, Eka H. E. D. Suchiman, Robert J. P. van der Wal, Rob G. H. H. Nelissen, Hailiang Mei, Yolande F. M. Ramos, Rodrigo Coutinho de Almeida & Ingrid Meulenbelt Background Failing of intrinsic [...]

By |2021-11-09T11:57:40+00:00August 15th, 2021|News, Papers artrose|0 Comments
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Whole-genome profiling of primary cutaneous anaplastic large cell lymphoma

Whole-genome profiling of primary cutaneous anaplastic large cell lymphoma | August 2021 | Haematologica Armando N. Bastidas Torres, Rutger C. Melchers, Liana van Grieken, Jacoba J. Out-Luiting, Hailiang Mei, Cedrick Agaser, Thomas B. Kuipers, Koen D. QuintRein Willemze, Maarten H. Vermeer, Cornelis P. Tensen Abstract Primary cutaneous anaplastic large cell lymphoma (pcALCL), a hematological neoplasm [...]

By |2021-11-09T13:19:40+00:00August 9th, 2021|papers SASC|0 Comments
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Nature Reviews Cardiology publication about T cells in atherosclerosis

Nature Reviews Cardiology publiceerde een artikel over het effect van vetzuren op T cellen en de implicaties voor atherosclerose onder leiding van LUMC-onderzoekers Wouter Jukema (Cardiologie) en Bas Heijmans (Biomedische Datawetenschappen). ‘Het is hoog tijd voor meer aandacht voor T cellen in cardiovasculair onderzoek, want atherosclerotische plaques zitten vol onstekings en T cellen [...]

By |2021-09-21T12:36:27+00:00July 20th, 2021|News, review|0 Comments
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Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells

Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells | July 2021 | Alejandro Rodríguez Ruiz, Amanda Dicks, Margo Tuerlings, Koen Schepers, Melissa van Pel, Rob G. H. H. Nelissen, Christian Freund, Christine L. Mummery, Valeria Orlova, Farshid Guilak, Ingrid Meulenbelt & Yolande F. M. Ramos [...]

By |2021-11-09T13:19:26+00:00July 20th, 2021|Papers artrose|0 Comments
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Moleculaire Epidemiologie  | copyright 2021

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