DISSERTATIONS

2023

Margo Tuerlings | 27-09-2023 | The bone and cartilage interplay in osteoarthritis: key to effective treatment strategy

2022

Alejandro Rodriguez Ruiz | 19-10-2022 | Osteoprotegerin: a double-edged sword in osteoarthritis development

Evelyn Houtman | 12-10-2022 | Aged human osteochondral explants as biomimetic osteoarthritis model: towards a druggable target in osteoarthritis

Marcella van Hoolwerff | 06-09-2022 |Dissecting cellular function of fibronectin in osteoarthritic cartilage

2020

Niels van den Berg | 22-01-2020 |Family matters: a genealogical inquiry into the familial component of longevity

2019

Rick Mourits | 17-12-2019 |Exceptional lives, extraordinary families. Familial clustering of longevity in the 19th and early-20th centuries

René Luijk | 16-10-2019 | From correlation to causation: Data-driven exploration of transcriptional regulation using population genomics

Jennifer Meessen | 26-09-2019 | Outcome of osteoarthritis and arthroplasty from patient perspective to molecular profiling.

2018

Wouter den Hollander | 29-03-2018 | On the relation between genetic variation and osteoarthritis

Jesse Krijthe | 17-01-2018 | Robust semi-supervised learning: projections, limits & constraints

2017

Roderik Slieker | 09-02-2017 | Charting the dynamic methylome across the human lifespan

Niels Bömer17-01-2017 | Thyroid hormone signaling in Osteoarthritis: early life events in late life disease

2016

Jonathan Vis | 21-12-2016 | Algorithms for the description of molecular sequences

Marjon Stijntjes | 12-10-2016 | Interactions of cognitive and physical ageing

Peter Thijssen | 01-09-2016 | Genetics and epigenetics of repeat derepression in human disease

2015

Yolande Ramos | 26-05-2015 | Osteoarthritis, a degenerative disease of the articular joints : towards the implementation of functional genomics in OA

Jenny van Dongen | 16-04-2015 | (Epi) genetics and twins

Erik van den Akker | 18-02-2015 | Computational biology in human aging : an omics data integration approach

Rudolf Talens | 08-01-2015 | Studies into epigenetic variation and its contribution to cardiovascular disease

2014

Joris Deelen | 25-06-2014 |Genetic and biomarker studies of human longevity

Anika Vaarhorst | 13-05-2014 |Genetic and metabolomic approaches for coronary heart disease risk prediction

2013

Willemijn Pastoors | 19-12-2013 | Transcriptomic studies in human ageing and longevity

Elmar Tobi | 29-10-2013 | Epigenetic differences after prenatal adversity : the Dutch hunger winter

2011

Maarten Rozing | 21-09-2011 | Endocrine and metabolic features of familial longevity : the Leiden Longevity Study

Rita Slof-Op ‘t Landt | 28-06-2011 | Genetic determinants of eating disorders

Renee Ruhaak | 24-03-2011 | Glycomics based biomarkers of the rate of aging : development and applications of high-throughput N-glycan analysis

2010

Steffan Bos | 15-09-2010 | Genes and mediators of inflammation and development in osteoarthritis

2007

Simon Mooijaart | 04-12-2007 | Genetic Determinants of Healthy Longevity

Maris Kuningas | 04-12-2007 | A Study into Genes Encoding Longevity in Humans

Josine Min | 17-01-2007 | Generalised Osteoarthritis: from Mendelian Disorder to Complex Disease

2006

Naghmeh Riyazi | 22-11-2006 | Familial osteorarthritis : risk factors and determinants of outcome

2005

Behrooz Alizadeh | 23-03-2005 | Osteoarthritis and hemochromatosis, a genetic epidemiological study

2004

Marian Beekman | 11-03-2004 | Towards mapping QTLs influencing parameters of lipid metabolism in human twins

2000

Bas Heijmans | 02-11-2000 | Common gene variants and mortality in the population at large

1997

Ingrid Meulenbelt | 28-10-1997 | Genetic Predisposing factors of Osteoarthritis

1993

Eline Slagboom | 30-11-1993 | Genomic instability and aging

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