Papers Ageing
Healthful plant-based diet associates with greater well-being in older adults
A shift towards a more plant-based diet is promoted as healthy as well as sustainable. Whether this also applies to older adults is however less clear: On one hand plant-based diets may lead to energy deficits among vulnerable older adults and therefore negatively impact [...]
Functional Changes of T-Cell Subsets with Age and CMV Infection
Hassouneh F, Goldeck D, Pera A, van Heemst D, Slagboom PE, Pawelec G, Solana R. | September 15th 2021 | Int J Mol Sci. 2021 Sep 15;22(18):9973. doi: 10.3390/ijms22189973. Abstract Cytomegalovirus (CMV) latent infection and aging contribute to alterations in the function and phenotype [...]
Improved selection of participants in genetic longevity studies: family scores revisited
Improved selection of participants in genetic longevity studies: family scores revisited | BMC Medicine | January 2021 Rodriguez-Girondo, M.; Berg, N. van den; Hof, M.H.; Beekman, M.; Slagboom, E. Background: Although human longevity tends to cluster within families, genetic studies on longevity have had limited success in identifying [...]
Long RNA Sequencing and Ribosome Profiling of Inflamed β-Cells Reveal an Extensive Translatome Landscape
Long RNA Sequencing and Ribosome Profiling of Inflamed β-Cells Reveal an Extensive Translatome Landscape | Diebetes | October 2021 Sofia Thomaidou, Roderick C Slieker, Arno R van der Slik, Jasper Boom, Flip Mulder, Amadeo Munoz-Garcia, Leen M 't Hart, Bobby Koeleman, Françoise Carlotti, Rob C Hoeben, Bart O Roep, Hailiang Mei, Arnaud Zaldumbide Abstract Type 1 diabetes [...]
Distinct molecular signatures of clinical clusters in people with type 2 diabetes: an IMI-RHAPSODY study
Distinct molecular signatures of clinical clusters in people with type 2 diabetes: an IMI-RHAPSODY study | Diabetes| August 2021 | Roderick C Slieker, Louise A Donnelly, Hugo Fitipaldi, Gerard A Bouland, Giuseppe N Giordano, Mikael Åkerlund, Mathias J Gerl, Emma Ahlqvist, Ashfaq Ali, Iulian Dragan, Petra Elders, Andreas Festa, Michael K Hansen, Amber A van der Heijden, Dina [...]
Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients
Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients | EMBO Mol Med | April 2021 Mirko Signorelli, Mitra Ebrahimpoor, Olga Veth, Kristina Hettne, Nisha Verwey, Raquel García-Rodríguez, Christa L Tanganyika-deWinter, Luz B Lopez Hernandez, Rosa Escobar Cedillo, Benjamín Gómez Díaz, Olafur T Magnusson, Hailiang Mei, Roula Tsonaka, Annemieke Aartsma-Rus, Pietro Spitali Abstract DMD [...]