Variants of FOXO3 and RPA3 genes affecting IGF-1 levels alter the risk of development of primary osteoarthritis

Variants of FOXO3 and RPA3 genes affecting IGF-1 levels alter the risk of development of primary osteoarthritis | January 2021 | European Journal of Endocrinology I C M Pelsma , K M J A Claessen, P E Slagboom, D van Heemst, A M Pereira, H M Kroon, Y F M Ramos, M Kloppenburg, N R Biermasz, and I M Meulenbelt Abstract Introduction Pathologically high growth hormone [...]

By |2021-09-15T13:34:34+00:00September 15th, 2021|Papers artrose|0 Comments

Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis

Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis | 20-02-2021 | Rheumatology and Therapy Evelyn Houtman, Marcella van Hoolwerff, Nico Lakenberg, Eka H. D. Suchiman, Enrike van der Linden-van der Zwaag, Rob G. H. H. Nelissen, Yolande F. M. Ramos & Ingrid Meulenbelt Introduction Likely due to ignored heterogeneity in disease pathophysiology, osteoarthritis (OA) [...]

By |2021-09-15T13:40:42+00:00September 15th, 2021|Papers artrose|0 Comments

Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants

Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants | 16-08-2021 | BMC Evelyn Houtman, Margo Tuerlings, Janne Riechelman, Eka H. E. D. Suchiman, Robert J. P. van der Wal, Rob G. H. H. Nelissen, Hailiang Mei, Yolande F. M. Ramos, Rodrigo Coutinho de Almeida & Ingrid Meulenbelt Background Failing of intrinsic [...]

By |2021-09-15T13:43:54+00:00September 15th, 2021|News, Papers artrose|0 Comments

Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility—Towards Identification of Applicable Early OA Biomarkers

Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility—Towards Identification of Applicable Early OA Biomarkers | Biomolecules| 13-09-2021 |  Yolande F. M. Ramos, Rodrigo Coutinho de Almeida, Nico Lakenberg, H. Eka D. Suchiman, Hailiang Mei, Margreet Kloppenburg, Rob G. H. H. Nelissen and Ingrid Meulenbelt To identify and validate circulating micro [...]

By |2021-09-14T14:30:54+00:00September 14th, 2021|Papers artrose|0 Comments
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