Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration

Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration | March 2021 | Rheumatology (Oxford, England) Rodrigo Coutinho de Almeida, Ahmed Mahfouz, Hailiang Mei, Evelyn Houtman, Wouter den Hollander, Jamie Soul, Eka Suchiman, Nico Lakenberg, Jennifer Meessen, Kasper Huetink, Rob G H H Nelissen, Yolande F M Ramos, Marcel Reinders, Ingrid [...]

By |2021-09-21T12:34:44+00:00September 20th, 2021|Papers artrose|0 Comments
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Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis

Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis | February 2021 |Rheumatology and Therapy Introduction Likely due to ignored heterogeneity in disease pathophysiology, osteoarthritis (OA) has become the most common disabling joint disease, without effective disease-modifying treatment causing a large social and economic burden. In this study [...]

By |2021-09-21T12:34:56+00:00September 20th, 2021|Papers artrose|0 Comments
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How does hip osteoarthritis differ from knee osteoarthritis?

Hall M, van der Esch M, Hinman RS, Peat G, de Zwart A, Quicke JG, Runhaar J, Knoop J, van der Leeden M, de Rooij M, Meulenbelt I, Vliet Vlieland T, Lems WF, Holden MA, Foster NE, Bennell KL. | Osteoarthritis Cartilage |  2021 Sep 29 | S1063-4584(21)00915-8. doi: 10.1016/j.joca.2021.09.010. Abstract Hip and knee [...]

By |2021-11-09T13:19:14+00:00September 19th, 2021|News, Papers artrose|0 Comments
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Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration

Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration | March 2021 | Rheumatology Rodrigo Coutinho de Almeida, Ahmed Mahfouz, Hailiang Mei, Evelyn Houtman, Wouter den Hollander, Jamie Soul, Eka Suchiman, Nico Lakenberg, Jennifer Meessen, Kasper Huetink ... Show more Abstract Objective To identify OA subtypes based on cartilage transcriptomic data in cartilage tissue and characterize their underlying pathophysiological processes and/or [...]

By |2021-09-21T12:35:43+00:00September 15th, 2021|Papers artrose|0 Comments
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Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility—Towards Identification of Applicable Early OA Biomarkers

Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility—Towards Identification of Applicable Early OA Biomarkers | Biomolecules| 13-09-2021 |  Yolande F. M. Ramos, Rodrigo Coutinho de Almeida, Nico Lakenberg, H. Eka D. Suchiman, Hailiang Mei, Margreet Kloppenburg, Rob G. H. H. Nelissen and Ingrid Meulenbelt To identify and validate circulating micro [...]

By |2021-09-14T14:30:54+00:00September 14th, 2021|Papers artrose|0 Comments
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Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants

Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants | 16-08-2021 | BMC Evelyn Houtman, Margo Tuerlings, Janne Riechelman, Eka H. E. D. Suchiman, Robert J. P. van der Wal, Rob G. H. H. Nelissen, Hailiang Mei, Yolande F. M. Ramos, Rodrigo Coutinho de Almeida & Ingrid Meulenbelt Background Failing of intrinsic [...]

By |2021-11-09T11:57:40+00:00August 15th, 2021|News, Papers artrose|0 Comments
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Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells

Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells | July 2021 | Alejandro Rodríguez Ruiz, Amanda Dicks, Margo Tuerlings, Koen Schepers, Melissa van Pel, Rob G. H. H. Nelissen, Christian Freund, Christine L. Mummery, Valeria Orlova, Farshid Guilak, Ingrid Meulenbelt & Yolande F. M. Ramos [...]

By |2021-11-09T13:19:26+00:00July 20th, 2021|Papers artrose|0 Comments
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Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls

Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls |  Clin exp Rheumothol | May/June 2021 Marije K Verheul, George M C Janssen, Arnoud de Ru, Gerrie Stoeken-Rijsbergen, E W Nivine Levarht, Joanneke C Kwekkeboom, Nils Bomer, Andreea Ioan-Facsinay, Ingrid Meulenbelt, Robert A Cordfunke, Jan W Drijfhout, Rene E M Toes, Peter A van Veelen, Leendert A Trouw Abstract Objectives: Antibodies targeting [...]

By |2021-11-09T13:20:23+00:00June 11th, 2021|Papers artrose|0 Comments
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Vitamin K antagonist anticoagulant usage is associated with increased incidence and progression of osteoarthritis

The role of TNFRSF11B in development of osteoarthritic cartilage | May 2021 | Annals of the Rheumatic diseases Cindy G Boer, Ingrid Szilagyi, N Long Nguyen, Tuhina Neogi, Ingrid Meulenbelt, M Arfan Ikram, André G Uitterlinden, Sita Bierma-Zeinstra, Bruno H Stricker, Joyce B van Meurs Correspondence to Dr Joyce B van Meurs, Internal Medicine, Erasmus Medical Center, [...]

By |2021-11-09T13:20:33+00:00May 20th, 2021|Papers artrose|0 Comments
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The role of TNFRSF11B in development of osteoarthritic cartilag

The role of TNFRSF11B in development of osteoarthritic cartilage | May 2021 | Rheumatology (Oxford) Alejandro Rodríguez Ruiz, Margo Tuerlings, Ankita Das, Rodrigo Coutinho de Almeida, H Eka Suchiman, Rob G H H Nelissen, Yolande F M Ramos, Ingrid Meulenbelt Abstract Objectives Osteoarthritis (OA) is a complex genetic disease with different risk factors contributing to its development. One of the genes, TNFRSF11B, previously [...]

By |2021-11-09T13:20:57+00:00May 20th, 2021|Papers artrose|0 Comments
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Moleculaire Epidemiologie  | copyright 2021

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