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Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells

Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells | July 2021 | Alejandro Rodríguez Ruiz, Amanda Dicks, Margo Tuerlings, Koen Schepers, Melissa van Pel, Rob G. H. H. Nelissen, Christian Freund, Christine L. Mummery, Valeria Orlova, Farshid Guilak, Ingrid Meulenbelt & Yolande F. M. Ramos [...]

By admin|2021-11-09T13:19:26+00:00July 20th, 2021|Papers artrose|0 Comments

Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls
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Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls

Papers artrose

Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls

Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls | Clin exp Rheumothol | May/June 2021 Marije K Verheul, George M C Janssen, Arnoud de Ru, Gerrie Stoeken-Rijsbergen, E W Nivine Levarht, Joanneke C Kwekkeboom, Nils Bomer, Andreea Ioan-Facsinay, Ingrid Meulenbelt, Robert A Cordfunke, Jan W Drijfhout, Rene E M Toes, Peter A van Veelen, Leendert A Trouw Abstract Objectives: Antibodies targeting [...]

By admin|2021-11-09T13:20:23+00:00June 11th, 2021|Papers artrose|0 Comments

Vitamin K antagonist anticoagulant usage is associated with increased incidence and progression of osteoarthritis

The role of TNFRSF11B in development of osteoarthritic cartilage | May 2021 | Annals of the Rheumatic diseases Cindy G Boer, Ingrid Szilagyi, N Long Nguyen, Tuhina Neogi, Ingrid Meulenbelt, M Arfan Ikram, André G Uitterlinden, Sita Bierma-Zeinstra, Bruno H Stricker, Joyce B van Meurs Correspondence to Dr Joyce B van Meurs, Internal Medicine, Erasmus Medical Center, [...]

By admin|2021-11-09T13:20:33+00:00May 20th, 2021|Papers artrose|0 Comments

The role of TNFRSF11B in development of osteoarthritic cartilag

The role of TNFRSF11B in development of osteoarthritic cartilage | May 2021 | Rheumatology (Oxford) Alejandro Rodríguez Ruiz, Margo Tuerlings, Ankita Das, Rodrigo Coutinho de Almeida, H Eka Suchiman, Rob G H H Nelissen, Yolande F M Ramos, Ingrid Meulenbelt Abstract Objectives Osteoarthritis (OA) is a complex genetic disease with different risk factors contributing to its development. One of the genes, TNFRSF11B, previously [...]

By admin|2021-11-09T13:20:57+00:00May 20th, 2021|Papers artrose|0 Comments

Censoring exosomal crosstalk in osteoarthritis
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Censoring exosomal crosstalk in osteoarthritis

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Censoring exosomal crosstalk in osteoarthritis

Censoring exosomal crosstalk in osteoarthritis |April 15 2021 | Nature Aging Ingrid Meulenbelt, Yolande F. M. Ramos, S. Rubina Baglio & D. Michiel Pegtel Abstract Using mouse models of osteoarthritis (OA), a new study finds that osteoclasts secrete exosomes that deliver miRNAs to chondrocytes, leading to an increase in metalloproteinase activity in cartilage. A bone-specific inhibitor [...]

By admin|2021-11-09T13:21:55+00:00April 15th, 2021|Papers artrose|0 Comments

Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis
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Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis

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Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis

Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis | 20-02-2021 | Rheumatology and Therapy Evelyn Houtman, Marcella van Hoolwerff, Nico Lakenberg, Eka H. D. Suchiman, Enrike van der Linden-van der Zwaag, Rob G. H. H. Nelissen, Yolande F. M. Ramos & Ingrid Meulenbelt Introduction Likely due to ignored heterogeneity in disease pathophysiology, osteoarthritis (OA) [...]

By admin|2021-09-15T13:40:42+00:00February 15th, 2021|Papers artrose|0 Comments

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies
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Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

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Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies | January 26 2021 | Addiction Biology Melissa A Munn-Chernoff, Emma C Johnson, Yi-Ling Chou, Jonathan R I Coleman, Laura M Thornton, ..................(including Meulenbelt I) Neale BM, Gerome Breen, Joel Gelernter, Howard J Edenberg, Cynthia M Bulik, Arpana Agrawal Abstract Eating disorders and substance use disorders frequently co-occur. [...]

By admin|2021-11-09T13:21:13+00:00February 9th, 2021|Papers artrose|0 Comments

Variants of FOXO3 and RPA3 genes affecting IGF-1 levels alter the risk of development of primary osteoarthritis
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Variants of FOXO3 and RPA3 genes affecting IGF-1 levels alter the risk of development of primary osteoarthritis

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Variants of FOXO3 and RPA3 genes affecting IGF-1 levels alter the risk of development of primary osteoarthritis

Variants of FOXO3 and RPA3 genes affecting IGF-1 levels alter the risk of development of primary osteoarthritis | January 2021 | European Journal of Endocrinology I C M Pelsma , K M J A Claessen, P E Slagboom, D van Heemst, A M Pereira, H M Kroon, Y F M Ramos, M Kloppenburg, N R Biermasz, and I M Meulenbelt Abstract Introduction Pathologically high growth hormone [...]

By admin|2021-11-09T13:22:05+00:00January 15th, 2021|Papers artrose|0 Comments