Papers SASC2021-11-09T13:26:21+00:00

Papers SASC

Depressive symptoms and plasma markers of Alzheimer’s disease and neurodegeneration: a coordinated meta-analysis of 8 cohort studies

Depressive symptoms and plasma markers of Alzheimer's disease and neurodegeneration: a coordinated meta-analysis of 8 cohort studies The Netherlands Consortium of Dementia Cohorts has performed a meta-analysis with 8 cohort studies to investigate the associations between depressive symptoms later in life and [...]

March 18th, 2024|Categories: News|

Healthful plant-based diet associates with greater well-being in older adults

A shift towards a more plant-based diet is promoted as healthy as well as sustainable. Whether this also applies to older adults is however less clear: On one hand plant-based diets may lead to energy deficits among vulnerable older adults and therefore negatively impact [...]

February 19th, 2024|Categories: News, Papers ageing|

New publication shows blood biomarkers for senescence endotypes in osteoarthritis patients

When cells reach a permanent growth arrest (Senescence) and resist death, this can result in numerous diseases, such as osteoarthritis. Here we show the presence of two different types of senescence in the blood metabolome of osteoarthritis patients. These blood metabolome patterns could function [...]

November 22nd, 2023|Categories: News, Papers artrose|

Aged human osteochondral explants as biomimetic osteoarthritis model: towards a druggable target in osteoarthritis

Evelyn Houtman | 22-10-2022 | Aged human osteochondral explants as biomimetic osteoarthritis model: towards a druggable target in osteoarthritis This thesis aims to increase the understanding of human osteoarthritis pathophysiology by developing reliable biomimetic ex vivo human osteochondral explant models and focussing on the [...]

November 22nd, 2023|Categories: thesis osteoarthritis|
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