Papers SASC
Exploring senescent chondrocytes during aging: sleeper AGEnts of osteoarthritis
Ilja Boone | 17-10-2025 | Exploring senescent chondrocytes during aging: sleeper AGEnts of osteoarthritis Osteoarthritis is a painful, age-related joint disease in which cellular senescence plays a central role. Senescent cells are retained from the active cell cycle and secrete harmful factors that contribute [...]
Invitation: MOLEPI symposium 2025
INVITATION: MOLEPI Symposium In celebration of our 25th ANNIVERSARY, we WILL BE hosting a special symposium to reflect on our journey and explore the future of molecular epidemiology 📅 THURSDAY, OCTOBER 30, 2025 ⌚ 13:30 – 18:00 📍 LUMC, BUILDING 1, LECTURE [...]
Invitation: MOLEPI reunion 2025
Invitation: MOLEPI reunion 2025 We will be hosting a reunion for all our former and present colleagues over the past 25 years 📅 SATURDAY NOVEMBER 1, 2025 ⌚ 14:00 – 18:00 📍 LUMC, BUILDING 2, The Restaurant Let’s celebrate! Sign up here: [...]
Effects of lipids on DNA methylation and gene expression of immune cells implicated in atherosclerosis
Koen Dekkers | 16-01-2025 | Effects of lipids on DNA methylation and gene expression of immune cells implicated in atherosclerosis Cardiovascular diseases, the leading cause of death worldwide, are often the result of atherosclerosis, a chronic inflammatory disease where lipids and immune cells accumulate [...]
Unravelling the developmental origins of disease: the power of mesenchymal stromal cells and monochorionic twins
Pia Todtenhaupt | 18-12-2024 | Unravelling the developmental origins of disease: the power of mesenchymal stromal cells and monochorionic twins This thesis explores the mechanisms linking adverse intrauterine environments to long-term health risks. Therefore, the Twinlife study was established. This study includes monochorionic (MC) twins [...]
The effects of triglycerides and fatty acids on T cells: role in atherosclerosis
Nathalie Reilly | 30-10-2024 | The effects of triglycerides and fatty acids on T cells: role in atherosclerosis Atherosclerosis, a leading cause of cardiovascular disease, is characterized by lipid accumulation in blood vessel walls. This chronic inflammation leads to plaque formation, increasing the risk [...]