Papers SASC
Osteoprotegerin: a double-edged sword in osteoarthritis development
Alejandro Rodríguez Ruiz | 22-09-2022 | Osteoprotegerin: a double-edged sword in osteoarthritis development To advance development of effective disease modifying OA treatments, a better understanding of its pathophysiological mechanisms is necessary. By studyinga family with early onset OA and high cartilage mineralization, a likely [...]
The bone and cartilage interplay in osteoarthritis: key to effective treatment strategy
Margo Tuerlings | 27-09-2023 | The bone and cartilage interplay in osteoarthritis: key to effective treatment strategy. Osteoarthritis (OA) is a prevalent age-related joint disease, determined by diverse changes in pathways maintaining articular cartilage and subchondral bone. This thesis aimed to identify and study [...]
Dissecting cellular function of fibronectin in osteoarthritic cartilage
Marcella van Hoolwerff | 06-09-2022 | Dissecting cellular function of fibronectin in osteoarthritic cartilage The aim of this thesis was to combine transcriptomics, genetics and human disease modelling to obtain further insight into molecular processes underlying osteoarthritis. More specifically, we aimed to elucidate the [...]
Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralization
Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralizationRheumatology (Oxford) | 2022 Apr 12:keac232 | doi: 10.1093/rheumatology/keac232Rodríguez Ruiz A, van Hoolwerff M, Sprangers S, Suchiman HED, Schoenmaker T, Dibbets-Schneider P, Bloem JL, Nelissen RGHH, Freund C, [...]
The role of TNFRSF11B in development of osteoarthritic cartilage.
The role of TNFRSF11B in development of osteoarthritic cartilage. Rheumatology (Oxford) | 2022 Feb 2;61(2):856-864. | doi: 10.1093/rheumatology/keab440 Rodríguez Ruiz A, Tuerlings M, Das A, Coutinho de Almeida R, Suchiman HED, Nelissen RGHH, Ramos YFM, Meulenbelt I. Abstract Objectives: OA is a complex genetic disease [...]
Publications 2022
PUBLICATIONS 2022 NOVEMBER OKTOBER SEPTEMBER AUGUSTUS JULI JUNI MEI APRIL MAART FEBRUARI JANUARI 2021 2020 2019 2018 QUESTIONS ABOUT OUR RESEARCH? ASK YOUR QUESTION [...]