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So far admin has created 174 blog entries.

Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses

Maxime M. Bos, Neil J. Goulding, Matthew A. Lee, Amy Hofman, Mariska Bot, René Pool, Lisanne S. Vijfhuizen, Xiang Zhang, Chihua Li, Rima Mustafa, Matt J. Neville, Ruifang Li-Gao, Stella Trompet, Marian Beekman, Nienke R. Biermasz, Dorret I. Boomsma, Irene de Boer, Constantinos Christodoulides, Abbas Dehghan, Ko Willems van Dijk, Ian Ford, Mohsen Ghanbari, [...]

Door |2021-10-11T12:10:21+00:00oktober 11th, 2021|Papers ageing|0 Reacties

Comprehensive diagnostics of acute myeloid leukemia by whole transcriptome RNA sequencing

Comprehensive diagnostics of acute myeloid leukemia by whole transcriptome RNA sequencing | January 2021 | Leukemia. 2021 Jan;35(1):47-61. doi: 10.1038/s41375-020-0762-8. Epub 2020 Mar 3. PMID: 32127641. Arindrarto W, Borràs DM, de Groen RAL, van den Berg RR, Locher IJ, van Diessen SAME, van der Holst R, van der Meijden ED, Honders MW, de Leeuw [...]

Door |2021-09-27T09:11:39+00:00september 27th, 2021|paper bioinformatica, Papers ageing|0 Reacties

The Transcriptome in Transition: Global Gene Expression Profiles of Young Adult Fruit Flies Depend More Strongly on Developmental Than Adult Diet

The Transcriptome in Transition: Global Gene Expression Profiles of Young Adult Fruit Flies Depend More Strongly on Developmental Than Adult Diet | March 2021 | Front. Ecol. Evol. May CM, van den Akker EB, Zwaan BJ Abstract Developmental diet is known to exert long-term effects on adult phenotypes in many animal species as well [...]

Door |2021-09-27T09:08:46+00:00september 27th, 2021|paper bioinformatica, Papers ageing|0 Reacties

The trans-ancestral genomic architecture of glycemic traits

The trans-ancestral genomic architecture of glycemic traits | Nat Genet | June 2021 Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, …, Erik van den Akker, …, Campbell A, Campbell H, Chang YC, de Geus EJC, Dehghan A. Abstract Glycemic traits are used to diagnose and monitor type [...]

Door |2021-09-27T09:02:45+00:00september 27th, 2021|paper bioinformatica, Papers ageing|0 Reacties

Discovering fiber type architecture over the entire muscle using data-driven analysis

Discovering fiber type architecture over the entire muscle using data-driven analysis | June 2021 | Cytometry A Bindellini D, Voortman LM, Olie Cyriel S, van Putten M, van den Akker EB, Raz V. Abstract Skeletal muscle function is inferred from the spatial arrangement of muscle fiber architecture, which corresponds to myofiber molecular and metabolic [...]

Door |2021-09-27T09:16:04+00:00september 27th, 2021|paper bioinformatica, Papers ageing|0 Reacties

Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: Relevance in infectious diseases and vaccination studies in human populations

Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: Relevance in infectious diseases and vaccination studies in human populations | Genes Immun | July 2021 Khatri I, Berkowska MA, van den Akker EB, Teodosio C, Reinders MJT, van Dongen JJM. Abstract Immunoglobulin (IG) loci harbor inter-individual allelic variants in many different germline IG variable, diversity [...]

Door |2021-09-27T08:54:53+00:00september 27th, 2021|paper bioinformatica, Papers ageing|0 Reacties

Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian

Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian | July 2021 | Leukemia. 2020 van den Akker EB, Makrodimitris S, Hulsman M, Brugman MH, Nikolic T, Bradley T, Waisfisz Q, Baas F, Jakobs ME, de Jong D, Slagboom PE, Staal FJT, Reinders MJT, Holstege H. Age-related Clonal hematopoiesis (ARCH) is an inevitable [...]

Door |2021-09-27T08:47:21+00:00september 27th, 2021|paper bioinformatica, Papers ageing|0 Reacties

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation | September 2021 |Nature Genetics Josine L Min, Gibran Hemani, Eilis Hannon, Koen F Dekkers, Juan Castillo-Fernandez, René Luijk, ................................., Tom R Gaunt, Jordana T Bell, Bastiaan T Heijmans, Jonathan Mill, Caroline L Relton  Abstract Characterizing genetic influences on DNA methylation (DNAm) provides an opportunity to understand mechanisms underpinning gene regulation and [...]

Door |2021-09-21T12:24:32+00:00september 21st, 2021|Papers epigenetica|0 Reacties

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations |September 2021 |Cell Cindy G Boer, Konstantinos Hatzikotoulas, Lorraine Southam, Lilja Stefánsdóttir, Yanfei Zhang, Rodrigo Coutinho de Almeida,........., Rob R G H H Nelissen, Margo Tuerlings, arcOGEN Consortium,.................., Ingrid Meulenbelt  , Ming Ta Michael Lee, Joyce B J van Meurs, Unnur Styrkársdóttir, Eleftheria Zeggini Abstract Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide [...]

Door |2021-09-21T12:10:53+00:00september 21st, 2021|Nieuws, Papers artrose|0 Reacties

Association of Thyroid Dysfunction With Cognitive Function: An Individual Participant Data Analysis

Association of Thyroid Dysfunction With Cognitive Function: An Individual Participant Data Analysis | August 2021 | JAMA Internal Medicin Nicolien A van Vliet, Diana van Heemst, Osvaldo P Almeida, Bjørn O Åsvold, Carole E Aubert, Jong Bin Bae, Linda E Barnes, Douglas C Bauer, Gerard J Blauw, Carol Brayne, Anne R Cappola, Graziano Ceresini, Hannie C Comijs , Jean-Francois Dartigues  ,Jean-Marie Degryse , Robin P F Dullaart, Marlise E A van Eersel  [...]

Door |2021-09-21T12:26:41+00:00september 21st, 2021|Nieuws, proefschrift ageing|0 Reacties
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