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So far admin has created 190 blog entries.

Distinct molecular signatures of clinical clusters in people with type 2 diabetes: an IMI-RHAPSODY study

Distinct molecular signatures of clinical clusters in people with type 2 diabetes: an IMI-RHAPSODY study | Diabetes| August 2021 | Roderick C Slieker, Louise A Donnelly, Hugo Fitipaldi, Gerard A Bouland, Giuseppe N Giordano, Mikael Åkerlund, Mathias J Gerl, Emma Ahlqvist, Ashfaq Ali, Iulian Dragan, Petra Elders, Andreas Festa, Michael K Hansen, Amber A van der Heijden, Dina Mansour Aly, Min Kim, Dmitry Kuznetsov, Florence Mehl, Christian Klose, Kai Simons, Imre Pavo, Timothy J Pullen, Tommi [...]

Door |2021-10-11T13:56:47+00:00oktober 11th, 2021|Papers ageing|0 Reacties

Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients

Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients | EMBO Mol Med | April 2021 Mirko Signorelli, Mitra Ebrahimpoor, Olga Veth, Kristina Hettne, Nisha Verwey, Raquel García-Rodríguez,  Christa L Tanganyika-deWinter, Luz B Lopez Hernandez, Rosa Escobar Cedillo, Benjamín Gómez Díaz, Olafur T Magnusson, Hailiang Mei, Roula Tsonaka, Annemieke Aartsma-Rus, Pietro Spitali Abstract DMD is a rare disorder characterized by progressive muscle degeneration and [...]

Door |2021-10-11T12:47:20+00:00oktober 11th, 2021|paper bioinformatica, Papers ageing|0 Reacties

CACTUS: integrating clonal architecture with genomic clustering and transcriptome profiling of single tumor cells

CACTUS: integrating clonal architecture with genomic clustering and transcriptome profiling of single tumor cells | Genome Med | 2021 Mar 24 Shadi Darvish Shafighi, Szymon M Kiełbasa, Julieta Sepúlveda-Yáñez, Ramin Monajemi,  Davy Cats, Hailiang Mei, Roberta Menafra, Susan Kloet, Hendrik Veelken,  Cornelis A M van Bergen, Ewa Szczurek  Abstract Background: Drawing genotype-to-phenotype maps in tumors is of paramount importance for understanding tumor heterogeneity. [...]

Door |2021-10-11T12:37:10+00:00oktober 11th, 2021|paper bioinformatica|0 Reacties

Cingulate networks associated with gray matter loss in Parkinson’s disease show high expression of cholinergic genes in the healthy brain

Cingulate networks associated with gray matter loss in Parkinson's disease show high expression of cholinergic genes in the healthy brain | Eur J Neurosci | June 2021 Arlin Keo, Oleh Dzyubachyk, Jeroen van der Grond, Anne Hafkemeijer, Wilma D J van de Berg, Jacobus J van Hilten,  Marcel J T Reinders, Ahmed Mahfouz  Abstract Structural covariance networks are able to identify [...]

Door |2021-10-11T12:30:09+00:00oktober 11th, 2021|paper bioinformatica|0 Reacties

CBA: Cluster-Guided Batch Alignment for Single Cell RNA-seq

CBA: Cluster-Guided Batch Alignment for Single Cell RNA-seq | April 2021 | Frontiers in Genetics |DOI:10.3389/fgene.2021.644211 Wenbo Yu, Ahmed Mahfouz, Marcel J.T. Reinders Abstract and Figures The power of single-cell RNA sequencing (scRNA-seq) in detecting cell heterogeneity or developmental process is becoming more and more evident every day. The granularity of this knowledge is further propelled [...]

Door |2022-04-26T13:46:20+00:00oktober 11th, 2021|paper bioinformatica, Papers LCBC|0 Reacties

Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses

Maxime M. Bos, Neil J. Goulding, Matthew A. Lee, Amy Hofman, Mariska Bot, René Pool, Lisanne S. Vijfhuizen, Xiang Zhang, Chihua Li, Rima Mustafa, Matt J. Neville, Ruifang Li-Gao, Stella Trompet, Marian Beekman, Nienke R. Biermasz, Dorret I. Boomsma, Irene de Boer, Constantinos Christodoulides, Abbas Dehghan, Ko Willems van Dijk, Ian Ford, Mohsen Ghanbari, [...]

Door |2021-10-11T12:10:21+00:00oktober 11th, 2021|Papers ageing|0 Reacties

Long RNA Sequencing and Ribosome Profiling of Inflamed β-Cells Reveal an Extensive Translatome Landscape

Long RNA Sequencing and Ribosome Profiling of Inflamed β-Cells Reveal an Extensive Translatome Landscape | October 2021 |American Diabetes Association Sofia Thomaidou, Roderick C. Slieker, Arno R. van der Slik, Jasper Boom, Flip Mulder, Amadeo Munoz-Garcia, Leen M. ‘t Hart, Bobby Koeleman, Françoise Carlotti, Rob C. Hoeben, Bart O. Roep, Hailiang Mei and Arnaud [...]

Door |2021-11-09T13:10:48+00:00oktober 9th, 2021|Nieuws, papers SASC|0 Reacties

Comprehensive diagnostics of acute myeloid leukemia by whole transcriptome RNA sequencing

Comprehensive diagnostics of acute myeloid leukemia by whole transcriptome RNA sequencing | January 2021 | Leukemia. 2021 Jan;35(1):47-61. doi: 10.1038/s41375-020-0762-8. Epub 2020 Mar 3. PMID: 32127641. Arindrarto W, Borràs DM, de Groen RAL, van den Berg RR, Locher IJ, van Diessen SAME, van der Holst R, van der Meijden ED, Honders MW, de Leeuw [...]

Door |2021-09-27T09:11:39+00:00september 27th, 2021|paper bioinformatica, Papers ageing|0 Reacties

The Transcriptome in Transition: Global Gene Expression Profiles of Young Adult Fruit Flies Depend More Strongly on Developmental Than Adult Diet

The Transcriptome in Transition: Global Gene Expression Profiles of Young Adult Fruit Flies Depend More Strongly on Developmental Than Adult Diet | March 2021 | Front. Ecol. Evol. May CM, van den Akker EB, Zwaan BJ Abstract Developmental diet is known to exert long-term effects on adult phenotypes in many animal species as well [...]

Door |2021-09-27T09:08:46+00:00september 27th, 2021|paper bioinformatica, Papers ageing|0 Reacties

The trans-ancestral genomic architecture of glycemic traits

The trans-ancestral genomic architecture of glycemic traits | Nat Genet | June 2021 Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, …, Erik van den Akker, …, Campbell A, Campbell H, Chang YC, de Geus EJC, Dehghan A. Abstract Glycemic traits are used to diagnose and monitor type [...]

Door |2021-09-27T09:02:45+00:00september 27th, 2021|paper bioinformatica, Papers ageing|0 Reacties
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