Publicaties Epigenetica
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation | September 2021 |Nature Genetics Josine L Min, Gibran Hemani, Eilis Hannon, Koen F Dekkers, Juan Castillo-Fernandez, René Luijk, ................................., Tom R Gaunt, Jordana T Bell, Bastiaan T Heijmans, Jonathan Mill, Caroline L Relton Abstract Characterizing genetic influences on DNA methylation (DNAm) [...]
Effects of fatty acids on T cell function: role in atherosclerosis Nathalie A Reilly 1 2,
Effects of fatty acids on T cell function: role in atherosclerosis | July 2021 | Nat Rev Cardiol Nathalie A Reilly, Esther Lutgens, Johan Kuiper, Bastiaan T Heijmans, J Wouter Jukema Abstract T cells are among the most common cell types present in atherosclerotic plaques and are increasingly being [...]
Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence
Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence | March 2021 | Human Molecular Genetics Rosa H Mulder, Alexander Neumann, Charlotte A M Cecil, Esther Walton, Lotte C Houtepen, Andrew J Simpkin, Jolien Rijlaarsdam, Bastiaan T Heijmans, Tom R Gaunt, Janine F Felix, Vincent W V Jaddoe, Marian J [...]
Omixer: multivariate and reproducible sample randomization to proactively counter batch effects in omics studies
Omixer: multivariate and reproducible sample randomization to proactively counter batch effects in omics studies | March 2021 | Bioinformatics Lucy Sinke, Davy Cats, Bastiaan T Heijmans Abstract Motivation: Batch effects heavily impact results in omics studies, causing bias and false positive results, but software to control them [...]
The tissue-specific aspect of genome-wide DNA methylation in newborn and placental tissues: implications for epigenetic epidemiologic studies
The tissue-specific aspect of genome-wide DNA methylation in newborn and placental tissues: implications for epigenetic epidemiologic studies |February 2021|J Dev Orig Health Dis Emilie M Herzog 1, Alex J Eggink, Sten P Willemsen, Roderick C Slieker, Janine F Felix, Andrew P Stubbs, Peter J van der Spek, Joyce B J van Meurs, Bastiaan [...]
Reply to ‘Early-life exposure to the Chinese Famine and subsequent T2DM’
Reply to 'Early-life exposure to the Chinese Famine and subsequent T2DM' | February 2021 | Nature reviews endocrinology Chihua Li, Elmar W Tobi, Bastiaan T Heijmans, L H Lumey