Publicaties Epigenetica
Respiratory distress syndrome and bronchopulmonary dysplasia after fetal growth restriction: Lessons from a natural experiment in identical twins
Respiratory distress syndrome and bronchopulmonary dysplasia after fetal growth restriction: Lessons from a natural experiment in identical twins | February 2021 | E Clinical Medicine Sophie G.Groene, Jip A.Spekman, Arjan B.te Pas, Bastiaan T.Heijmans, Monique C.Haak, Jeanine M.M.van Klink, Arno A.W.Roest, Enrico Lopriore Abstract Background [...]
Het effect van genetica op epigenetica gepubliceerd in Nature Genetics – 6 september 2021
Nature Genetics | 6 september 2021 Het effect van genetica op epigenetica gepubliceerd in Nature Genetics Nature Genetics publiceerde deze week het resultaat van een grootschalige internationale studie naar de invloed van genetica op DNA methylatie, een essentiële epigenetische factor. Het was het resultaat [...]
Genetics and epigenetics of repeat derepression in human disease
Peter Thijssen| 01-09-2016 | Genetics and epigenetics of repeat derepression in human disease A large part of the human genome consists of repetitive DNA. In this thesis two human diseases have been studied in which deregulation of repetitive DNA is a central feature: facioscapulohumeral [...]
Persistent epigenetic differences associated with prenatal exposure to famine in humans
Proc Natl Acad Sci USA | November 2009 Abstract Extensive epidemiologic studies have suggested that adult disease risk is associated with adverse environmental conditions early in development. Although the mechanisms behind these relationships are unclear, an involvement of epigenetic dysregulation has been hypothesized. [...]
Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array
Epigenetics & Chromatin | Volume 6 | article numebr 26 | 06 August 2013 Abstract DNA methylation has been recognized as a key mechanism in cell differentiation. Various studies have compared tissues to characterize epigenetically regulated genomic regions, but due to differences in [...]