Proefschriften Ageing2021-07-20T08:16:33+00:00

Proefschriften ageing

Family matters: a genealogical inquiry into the familial component of longevity

Niels van den Berg | 22-01-2020 | Family matters: a genealogical inquiry into the familial component of longevity Identifying genes that code for proteins associated to longevity is an important aspect of aging research. These longevity genes likely represent key mechanisms of a life-long decreased [...]

juli 5th, 2021|Categories: proefschrift ageing|

Rick Mourits | 17-12-2019 | Exceptional lives, extraordinary families. Familial clustering of longevity in the 19th and early-20th centuries On 4 October 1829, Leendert Wisse was born in Meliskerke, a small, rural town on the island of Walcheren in Zeeland. In many ways, Leendert’s life [...]

juli 5th, 2021|Categories: proefschrift ageing|

From correlation to causation: Data-driven exploration of transcriptional regulation using population genomics

René Luijk | 16-10-2019 |A Study into Genes Encoding Longevity in Humans In this thesis, we aimed to better understand how genetic variation affect the processes underlying health and disease, as trait-associated genetic variants are often located in non-coding regions. This hampers their interpretability, [...]

juli 5th, 2021|Categories: proefschrift ageing|

Robust semi-supervised learning: projections, limits & constraints

Jesse Krijthe | 07-01-2018 | Robust semi-supervised learning: projections, limits & constraints In many domains of science and society, the amount of data being gathered is increasing rapidly. To estimate input-output relationships that are often of interest, supervised learning techniques rely on a specific [...]

juli 5th, 2021|Categories: proefschrift ageing|

Algorithms for the Description of Molecular Sequences

Jonathan Vis | 21-12-2016 | Algorithms for the Description of Molecular Sequences Unambiguous sequence variant descriptions are important in reporting the outcome of clinical diagnostic DNA tests. The standard nomenclature of the Human Genome Variation Society (HGVS) describes the observed variant sequence relative to a given reference [...]

juli 5th, 2021|Categories: proefschrift ageing|

Interactions of cognitive and physical ageing

Marjon Stijntjes | 12-10-2016 |A Study into Genes Encoding Longevity in Humans Human ageing is characterized by a gradual decline in cognitive and physical performance strongly determining someone’s functional abilities and quality of life. In this thesis, insights into these age-related changes and most [...]

juli 5th, 2021|Categories: proefschrift ageing|
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