Publicaties LCBC
1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints
1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints | 2022 Jan;75:103764 | EBioMedicine | doi: 10.1016/j.ebiom.2021.103764 Bizzarri D, Reinders MJT, Beekman M, Slagboom PE, BBMRI-NL, van den Akker EB. Abstract Background: Missing or incomplete phenotypic information can severely deteriorate the statistical power in [...]
CBA: Cluster-Guided Batch Alignment for Single Cell RNA-seq
CBA: Cluster-Guided Batch Alignment for Single Cell RNA-seq | April 2021 | Frontiers in Genetics |DOI:10.3389/fgene.2021.644211 Wenbo Yu, Ahmed Mahfouz, Marcel J.T. Reinders Abstract and Figures The power of single-cell RNA sequencing (scRNA-seq) in detecting cell heterogeneity or developmental process is becoming more and more evident [...]
Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian
Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian | 12-11-2020 | Leukemia Erik B. van den Akker, Stavros Makrodimitris, Marc Hulsman, Martijn H. Brugman, Tatjana Nikolic, Ted Bradley, Quinten Waisfisz, Frank Baas, Marja E. Jakobs, Daphne de Jong, P. Eline Slagboom, Frank J. T. Staal, Marcel J. T. Reinders & Henne Holstege Age-related Clonal hematopoiesis [...]