PAPERS2021-06-24T09:52:19+00:00

Papers 

New publication shows blood biomarkers for senescence endotypes in osteoarthritis patients

When cells reach a permanent growth arrest (Senescence) and resist death, this can result in numerous diseases, such as osteoarthritis. Here we show the presence of two different types of senescence in [...]

november 22nd, 2023|Categories: Nieuws, Papers artrose|

Aged human osteochondral explants as biomimetic osteoarthritis model: towards a druggable target in osteoarthritis

Evelyn Houtman | 22-10-2022 | Aged human osteochondral explants as biomimetic osteoarthritis model: towards a druggable target in osteoarthritis This thesis aims to increase the understanding of human osteoarthritis pathophysiology by developing [...]

november 22nd, 2023|Categories: proefschrift artrose|

Osteoprotegerin: a double-edged sword in osteoarthritis development

Alejandro Rodríguez Ruiz | 22-09-2022 | Osteoprotegerin: a double-edged sword in osteoarthritis development To advance development of effective disease modifying OA treatments, a better understanding of its pathophysiological mechanisms is necessary. By [...]

november 22nd, 2023|Categories: proefschrift artrose|

The bone and cartilage interplay in osteoarthritis: key to effective treatment strategy

Margo Tuerlings | 27-09-2023 | The bone and cartilage interplay in osteoarthritis: key to effective treatment strategy. Osteoarthritis (OA) is a prevalent age-related joint disease, determined by diverse changes in pathways maintaining [...]

november 21st, 2023|Categories: proefschrift artrose|

Dissecting cellular function of fibronectin in osteoarthritic cartilage

Marcella van Hoolwerff | 06-09-2022 | Dissecting cellular function of fibronectin in osteoarthritic cartilage The aim of this thesis was to combine transcriptomics, genetics and human disease modelling to obtain further insight [...]

november 21st, 2023|Categories: proefschrift artrose|

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