Dissecting cellular function of fibronectin in osteoarthritic cartilage
Marcella van Hoolwerff | 06-09-2022 | Dissecting cellular function of fibronectin in osteoarthritic cartilage The aim of this thesis was to combine transcriptomics, genetics and human disease modelling to obtain further insight into molecular [...]
Doe mee aan de gratis mini-cursus ‘Vitaal en gezond ouder worden’
Doe mee aan de gratis mini-cursus ‘Vitaal en gezond ouder worden’ Wat is veroudering eigenlijk? Komt er straks een anti-verouderingspil? Hoeveel moet ik bewegen en wat kan ik het beste eten? In de gratis [...]
1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints
1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints | 2022 Jan;75:103764 | EBioMedicine | doi: 10.1016/j.ebiom.2021.103764 Bizzarri D, Reinders MJT, Beekman M, Slagboom PE, BBMRI-NL, van den Akker EB. Abstract Background: Missing or [...]
A human in vitro 3D neo-cartilage model to explore the response of OA risk genes to hyper-physiological mechanical stress
A human in vitro 3D neo-cartilage model to explore the response of OA risk genes to hyper-physiological mechanical stress | Osteoarthritis and Cartilage Open| 4(1) (2022) 100231 | doi: 10.1016/j.ocarto.2021.100231 R.G.M. Timmermans, N.G.C. Bloks, [...]
A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis
A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis | Hum Mol Genet | 2022 Jan 28:ddac017 | doi: 10.1093/hmg/ddac017. Katsoula G, Steinberg J, Tuerlings M, de Almeida [...]
ANP32A represses Wnt signaling across tissues thereby protecting against osteoarthritis and heart disease.
ANP32A represses Wnt signaling across tissues thereby protecting against osteoarthritis and heart disease| Osteoarthritis Cartilage | 2022 Feb 25:S1063-4584(22)00650-1 | doi: 10.1016/j.joca.2022.02.615 Monteagudo S, Cornelis FMF, Wang X, de Roover A, Peeters T, Quintiens [...]