PAPERS2021-07-20T06:56:53+00:00

Papers

Dissecting cellular function of fibronectin in osteoarthritic cartilage

Marcella van Hoolwerff | 06-09-2022 | Dissecting cellular function of fibronectin in osteoarthritic cartilage The aim of this thesis was to combine transcriptomics, genetics and human disease modelling to obtain further insight [...]

November 21st, 2023|Categories: thesis osteoarthritis|

Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralization

Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralizationRheumatology (Oxford) | 2022 Apr 12:keac232 | doi: 10.1093/rheumatology/keac232Rodríguez Ruiz A, van Hoolwerff M, Sprangers S, [...]

April 19th, 2022|Categories: News, Papers artrose|

The role of TNFRSF11B in development of osteoarthritic cartilage.

The role of TNFRSF11B in development of osteoarthritic cartilage. Rheumatology (Oxford) |  2022 Feb 2;61(2):856-864. | doi: 10.1093/rheumatology/keab440 Rodríguez Ruiz A, Tuerlings M, Das A, Coutinho de Almeida R, Suchiman HED, Nelissen [...]

April 19th, 2022|Categories: News, Papers artrose|

Leiden master’s student cracks epigenetic clock that predicts age – newsitem LUMC 14-01-2022

Researchers can accurately determine how old a person is based on the calibration of the DNA. To do this, they use a so-called epigenetic clock. Master's student Thomas Jonkman has now, nine [...]

January 17th, 2022|Categories: News, News|

High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II

High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II I| November 5 - 2021 | Science Advances Marcella van Hoolwerff, Alejandro Rodríguez Ruiz, Marga Bouma,  H. [...]

November 9th, 2021|Categories: News, Papers artrose|

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