Papers Bio-Informatics
The trans-ancestral genomic architecture of glycemic traits
The trans-ancestral genomic architecture of glycemic traits | Nat Genet | June 2021 Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, …, Erik van den Akker, …, Campbell A, Campbell H, Chang YC, de Geus [...]
Discovering fiber type architecture over the entire muscle using data-driven analysis
Discovering fiber type architecture over the entire muscle using data-driven analysis | June 2021 | Cytometry A Bindellini D, Voortman LM, Olie Cyriel S, van Putten M, van den Akker EB, Raz V. Abstract Skeletal muscle function is inferred from the [...]
Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: Relevance in infectious diseases and vaccination studies in human populations GalleryPopulation matched (pm) germline allelic variants of immunoglobulin (IG) loci: Relevance in infectious diseases and vaccination studies in human populations
Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: Relevance in infectious diseases and vaccination studies in human populations
Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: Relevance in infectious diseases and vaccination studies in human populations | Genes Immun | July 2021 Khatri I, Berkowska MA, van den Akker EB, Teodosio C, Reinders MJT, van Dongen JJM. [...]
Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian
Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian | July 2021 | Leukemia. 2020 van den Akker EB, Makrodimitris S, Hulsman M, Brugman MH, Nikolic T, Bradley T, Waisfisz Q, Baas F, Jakobs ME, de Jong D, Slagboom PE, [...]
Omixer: multivariate and reproducible sample randomization to proactively counter batch effects in omics studies
Omixer: multivariate and reproducible sample randomization to proactively counter batch effects in omics studies | March 2021 | Bioinformatics Lucy Sinke, Davy Cats, Bastiaan T Heijmans Abstract Motivation: Batch effects heavily impact results in omics studies, causing bias and false positive results, but software [...]