Genetic determinants of eating disorders
Rita Slof-Op 't Landt| 04-12-2007 | Genetic determinants of eating disorders In this thesis, a series of studies on different aspects of the genetics of eating disorders is presented. The heritability of disordered eating [...]
Glycomics based biomarkers of the rate of aging: Development and applications of high throughput N-glycan analysis
Renée Ruhaak | 24-03-2011 | Glycomics based biomarkers of the rate of aging: Development and applications of high throughput N-glycan analysis Markers for longevity, which reflect the health condition and predict healthspan are extremely [...]
Genes and Mediators of Inflammation and Development in Osteoarthritis
Steffan Bos | 15-09-2010 | Genes and Mediators of Inflammation and Development in Osteoarthritis Osteoarthritis (OA) mainly affects the articular cartilage covering the bones. In this thesis we investigated the relation between levels of [...]
Genetic Determinants of Healthy Longevity
Simon Mooijaart| 04-12-2007 | Genetic Determinants of Healthy Longevity Lifespan in under genetic control. In this thesis we translated genes regulating lifespan in model organisms to humans. First we identified DAF-12 as a critical [...]
A Study into Genes Encoding Longevity in Humans
Maris Kuningas | 04-12-2007 |A Study into Genes Encoding Longevity in Humans The lifespan of an organism is determined by a complex network of environmental-, genetic- and stochastic factors. Each of these components contributes to [...]
Generalised Osteoarthritis: from Mendelian Disorder to Complex Disease
Josine Min | 17-01-2007| Generalised Osteoarthritis: from Mendelian Disorder to Complex Disease Osteoarthritis (OA) is a prevalent and complex disorder with a high hereditary probability. Previous genetic research into OA has yielded several common gene [...]