Rudolf Talens | 08-01-2015 |Studies into epigenetic variation and its contribution to cardiovascular disease  Epigenetic mechanisms regulate cellular gene expression potential without changing the genetic code. Like the genetic sequence, epigenetic marks are faithfully transmitted during mitosis and are generally stable in differentiated cells, [...]

Rene Luijk | 16-10-2019 | From correlation to causation: Data-driven exploration of transcriptional regulation using population genomics In this thesis, we aimed to better understand how genetic variation affect the processes underlying health and disease, as trait-associated genetic variants are often located in non-coding [...]

Elmar Tobi | 29-10-2013 | Epigenetic differences after prenatal adversity: The Dutch Hunger Winter This thesis is a study on the link between early development and adult health. Studies in animal models indicate that so-called epigenetic marks may be influenced by nutrition during development, [...]