Papers
A Study into Genes Encoding Longevity in Humans
Maris Kuningas | 04-12-2007 |A Study into Genes Encoding Longevity in Humans The lifespan of an organism is determined by a complex network of environmental-, genetic- and stochastic factors. Each of these components [...]
Generalised Osteoarthritis: from Mendelian Disorder to Complex Disease
Josine Min | 17-01-2007| Generalised Osteoarthritis: from Mendelian Disorder to Complex Disease Osteoarthritis (OA) is a prevalent and complex disorder with a high hereditary probability. Previous genetic research into OA has yielded several [...]
Familial osteorarthritis : risk factors and determinants of outcome
Naghmeh Riyazi | 22-11-2006 | Familial osteorarthritis : risk factors and determinants of outcome Osteoarthritis (OA) refers to a heterogeneous group of conditions. This thesis focuses on OA with a hereditary background; [...]
Osteoarthritis and hemochromatosis, a genetic epidemiological study
B.Z. Alizadeh (Behrooz)| 23-03-2005 | Osteoarthritis and hemochromatosis, a genetic epidemiological study Osteoarthritis (OA) refers to a heterogeneous group of distinct diseases which express a common radiographic and clinical phenotype at [...]
Prestigious ZonMw Open Competition grant awarded to LUMC, VU and RIVM
Prestigious ZonMw Open Competition grant awarded to LUMC, Vu and RIVM Our life expectancy is increasing worldwide, but the years we spend in good health are lagging behind. People from [...]
Persistent epigenetic differences associated with prenatal exposure to famine in humans
Proc Natl Acad Sci USA | November 2009 Abstract Extensive epidemiologic studies have suggested that adult disease risk is associated with adverse environmental conditions early in development. Although the mechanisms behind [...]