Papers SASC
Familial osteorarthritis : risk factors and determinants of outcome
Naghmeh Riyazi | 22-11-2006 | Familial osteorarthritis : risk factors and determinants of outcome Osteoarthritis (OA) refers to a heterogeneous group of conditions. This thesis focuses on OA with a hereditary background; Familial OA at multiple joint sites and radiological hand OA at middle [...]
Osteoarthritis and hemochromatosis, a genetic epidemiological study
B.Z. Alizadeh (Behrooz)| 23-03-2005 | Osteoarthritis and hemochromatosis, a genetic epidemiological study Osteoarthritis (OA) refers to a heterogeneous group of distinct diseases which express a common radiographic and clinical phenotype at diarthrodial joints.It is the leading cause of pain and disability in the [...]
Prestigious ZonMw Open Competition grant awarded to LUMC, VU and RIVM
Prestigious ZonMw Open Competition grant awarded to LUMC, Vu and RIVM Our life expectancy is increasing worldwide, but the years we spend in good health are lagging behind. People from long-lived families often reach exceptionally old ages without disease. How is that [...]
Persistent epigenetic differences associated with prenatal exposure to famine in humans
Proc Natl Acad Sci USA | November 2009 Abstract Extensive epidemiologic studies have suggested that adult disease risk is associated with adverse environmental conditions early in development. Although the mechanisms behind these relationships are unclear, an involvement of epigenetic dysregulation has been hypothesized. [...]
Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array
Epigenetics & Chromatin | Volume 6 | article numebr 26 | 06 August 2013 Abstract DNA methylation has been recognized as a key mechanism in cell differentiation. Various studies have compared tissues to characterize epigenetically regulated genomic regions, but due to differences in [...]
Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls
Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls | Clin exp Rheumothol | May/June 2021 Marije K Verheul, George M C Janssen, Arnoud de Ru, Gerrie Stoeken-Rijsbergen, E W Nivine Levarht, Joanneke C Kwekkeboom, Nils Bomer, Andreea Ioan-Facsinay, Ingrid Meulenbelt, Robert A Cordfunke, Jan W Drijfhout, Rene E [...]