Glycomics based biomarkers of the rate of aging: Development and applications of high throughput N-glycan analysis

Renée Ruhaak | 24-03-2011 | Glycomics based biomarkers of the rate of aging: Development and applications of high throughput N-glycan analysis Markers for longevity, which reflect the health condition and predict healthspan are extremely scarce. Such markers are, however, valuable in aging research. Protein N-glycosylation is an important post-translational modification, which has been shown [...]

Door |2021-07-05T09:25:03+00:00juli 5th, 2021|proefschrift ageing|0 Reacties

Genetic Determinants of Healthy Longevity

Simon Mooijaart| 04-12-2007 | Genetic Determinants of Healthy Longevity Lifespan in under genetic control. In this thesis we translated genes regulating lifespan in model organisms to humans. First we identified DAF-12 as a critical gene for lifespan regulation in the nematode worm C. elegans. Then we found that the Liver X Receptors and the [...]

Door |2021-07-05T09:13:34+00:00juli 5th, 2021|proefschrift ageing|0 Reacties

A Study into Genes Encoding Longevity in Humans

Maris Kuningas | 04-12-2007 |A Study into Genes Encoding Longevity in Humans The lifespan of an organism is determined by a complex network of environmental-, genetic- and stochastic factors. Each of these components contributes to the wide variability in lifespan between and within species. In recent years, it has been shown that 20-30 % of [...]

Door |2021-07-05T09:38:37+00:00juli 5th, 2021|proefschrift ageing|0 Reacties
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