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Leiden master’s student cracks epigenetic clock that predicts age – newsitem LUMC 14-01-2022
Researchers can accurately determine how old a person is based on the calibration of the DNA. To do this, they use a so-called epigenetic clock. Master's student Thomas Jonkman has now, nine years after the discovery, unravelled how this clock exactly works: it turns out to keep track of the ageing of our immune [...]
High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II
High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II I| November 5 - 2021 | Science Advances Marcella van Hoolwerff, Alejandro Rodríguez Ruiz, Marga Bouma, H. Eka D. Suchiman, Roman i. Koning, Carolina r. Jost, Aat a. Mulder, Christian Freund, Farshid Guilak, Yolande F. M. Ramos and Ingrid [...]