Correction for both common and rare cell types in blood is important to identify genes that correlate with age | March 2021 | BMC Genomics Damiano Pellegrino-Coppola, Annique Claringbould, Maartje Stutvoet, BIOS Consortium, Dorret I. Boomsma, M. Arfan Ikram, P. Eline Slagboom, Harm-Jan Westra & Lude Franke Abstract BACKGROUND: Aging is a multifactorial process that [...]
Associations of Cytomegalovirus Infection With All-Cause and Cardiovascular Mortality in Multiple Observational Cohort Studies of Older Adults | February 2021 | The Journal of Infectious Diseases Sijia Chen, Graham Pawelec, Stella Trompet, David Goldeck, Laust H. Mortensen, P. Eline Slagboom, Kaare Christensen, Jacobijn Gussekloo, Patricia Kearney, Brendan M. Buckley, Ian Ford, J. Wouter Jukema, Rudi G.J. Westendorp, Andrea B. [...]
Variants of FOXO3 and RPA3 genes affecting IGF-1 levels alter the risk of development of primary osteoarthritis | January 2021 | European Journal of Endocrinology I C M Pelsma, K M J A Claessen, P E Slagboom, D van Heemst, A M Pereira, H M Kroon, Y F M Ramos, M Kloppenburg, N R Biermasz, I M Meulenbelt Abstract Introduction: Pathologically high growth hormone [...]
Families in comparison: An individual-level comparison of life-course and family reconstructions between population and vital event registers | 12-02-2020 | A Journal of Demography Niels van den Berg, Ingrid K. van Dijk, Rick J. Mourits, P. Eline Slagboom, Angelique A.P.O. Janssens & Kees Mandemakers Identifying genes that code for proteins associated to longevity is [...]
Willemijn Passtoors | 19-12-2013 | Transcriptomic studies in human ageing and longevity The aim of this thesis was to identify in the human blood transcriptome, relevant pathways and potential biomarker profiles that associate with chronological age and discriminate between __healthy agers__ from long-lived families and normative ageing controls. Such profiles may harbor determinants of [...]
