Publicaties Bio-Informatica
Improved Sézary cell detection and novel insights into immunophenotypic and molecular heterogeneity in Sézary syndrome
Improved Sézary cell detection and novel insights into immunophenotypic and molecular heterogeneity in Sézary syndrome | July 2021 | Safa Najidh, Cornelis P Tensen, Alita J. van der Sluijs-Gelling, Cristina Teodosio, Davy Cats, Hailiang Mei, Thomas B. Kuipers, Jacoba J. Out-Luiting, Willem H. Zoutman, Thorbald van Hall, [...]
Family matters: a genealogical inquiry into the familial component of longevity
Niels van den Berg | 22-01-2020 | Family matters: a genealogical inquiry into the familial component of longevity Identifying genes that code for proteins associated to longevity is an important aspect of aging research. These longevity genes likely represent key mechanisms of [...]
From correlation to causation: Data-driven exploration of transcriptional regulation using population genomics
René Luijk | 16-10-2019 |A Study into Genes Encoding Longevity in Humans In this thesis, we aimed to better understand how genetic variation affect the processes underlying health and disease, as trait-associated genetic variants are often located in non-coding regions. This [...]
Outcome of osteoarthritis and arthroplasty from patient perspective to molecular profiling.
Jennifer Meessen | 26-09-2019 | Outcome of osteoarthritis and arthroplasty from patient perspective to molecular profiling With increasing life expectancy, the incidence and burden of osteoarthritis on society increases. Currently, no treatment for end-stage symptomatic osteoarthritis is available and when symptoms [...]
On the relation between genetic variation and osteoarthritis
Wouter den Hollander | 29-03-2018 | On the relation between genetic variation and osteoarthritis In dit proefschrift worden de moleculaire mechanismen behandeld die onderliggend zijn aan artrose. Specifiek wordt genoomwijd onderzocht welke genen anders tot expressie komen in aangedaan vergeleken met gezond [...]